Cannabidiol, or CBD, is one of the key ingredients of cannabis that has attracted considerable interest in the scientific community and doctors in recent years. Unlike THC, this compound does not show the psychoactive properties with which marijuana is associated, which is a species different from that of cannabis.
How was CBD discovered?
CBD was first isolated in the 1940s, when the rampaging Harry Anslinger, then director of the Federal Drug Bureau of the US Treasury, led his anti-cannabis crusade nationwide, better known as the Reefer Madness, in the best possible way. However, it was not until the 1960s that it was possible to describe its chemical structure in detail.
Interestingly, the discovery of CBD coincided with the isolation of THC, which was part of a larger experiment by a pair of Israeli-American researchers, Roger Adams and Raphael Mechoulum. To this day, it is not known which of them was in fact the “father” of this scientific success, but anyway, it’s nice that more or less consciously, they laid the groundwork for restoring cannabis to its good name.
What is CBD, and how does it work?
Our brain is made up of approximately 100 billion cells called neurons. Each of them communicates with its neighbor through special structures called synapses. A synapse is such a simple ‘device’ in the brain consisting of a transmitter and a receptor. When the synapse is inactive – we are sitting, there is peace, nothing happens – there is no interaction between the transmitter and the receptor.
And when the synapse is activated, the messenger sends out molecules that travel across the synapse as chemical messengers to attach themselves to the receptor. Such communication triggers specific reactions in the body or the brain. CBD – like the other cannabinoids – works on almost the same principle. Let’s see which receptors CBD interacts with:
- CB1 and CB2 (cannabinoid receptors in the endocannabinoid system)
- Adenosine receptors
- Serotonin receptors
- Vanilloid receptors
Cannabidiol acts at the molecular level and helps to activate the necessary parts of the nervous system and receptors in order to obtain a beneficial effect on the entire body. it is worth noting the special psychological and psychophysical functions that allow a person to feel better after taking cannabidiol. Despite the fact that there is still no percentage confirmation of all known effects, this is still one of the most gentle ways to help patients with a non-invasive method.
Health benefits of CBD
Okay, we know what CBD is, how it was discovered, how it reacts with the body. Let’s take a look at what interests us most – its medical properties. Cannabidiol is characterized by the following actions:
- The anti-inflammatory;
- Anxiolytics and anti-depressants;
Given the versatility of Cannabidiol, you are probably wondering what its use might be in treating disease. Let’s review the most important scientific discoveries regarding the use of CBD in the treatment of various diseases, ranging from simple headache, through anxiety and psychosis, to autoimmune diseases and neurodegenerative diseases.
Does CBD have side effects?
Despite numerous scientific studies on the wide range of CBD servings and its use, no adverse effects have been identified. It is increasingly emphasized that CBD is safe even in large amounts, and what’s more, it is very well tolerated by the human body. That’s why CBD oil for sale is so important.
Possible side effects include nausea, dry mouth, headache, and general weakness. A small number of people have these problems. However, you should get medical advice before using CBD.
Natural CBD for health
CBD is not psychoactive and, therefore, not suitable for recreational use. However, its properties are of interest to doctors precisely for this reason. Thanks to the wide spectrum of interactions on many levels, its therapeutic possibilities are almost unlimited. The list of diseases for which it helps is long because a deficiency of CBD causes most of them and other cannabinoids naturally occurring only in cannabis and our bodies. Limiting access to cannabis in the 20th century had a significant impact on the deterioration of many societies’ health.
CBD preparations are used in the treatment of most civilizations and neurological diseases. Here are another CBD oil benefits. Cannabidiol has a beneficial pharmacological effect on both the body and mind of the user.
Cannabidiol in its pure form helps to overcome various psychological problems of the body As well as a number of physical problems point For example, there are many studies that have shown the help of cannabidiol in overcoming muscle spasms, inflammation and swelling. It is also a good option that can replace sedatives. Cannabidiol can calm depressed people and help with insomnia. There are also many other studies that do not yet have one hundred percent confirmation, but already show a positive trend in the use of cannabidiol in various fields.
Natural CBD provides much better treatment results than conventional synthetic agents, but unlike them, CBD oil effects can’t harm people. Therefore, it is appreciated by a growing group of doctors, but above all, by patients for whom conventional medicine has proved ineffective.
How to use CBD?
Cannabidiol is also a strong and mild medicinal substance that can bring very positive health effects on the body, not only humans but also animals. But how do you use CBD to get the best possible performance? There are many ways to consume CBD from plants. Choose one of them, depending on the desired result. The most important of them are described below:
- CBD drops or pastes orally under the tongue – the most popular and used method of administering CBD. Hemp oil allows you to regulate the dose to the drops precisely. It ensures high bioavailability and quick absorption, so the effects are visible within 15 minutes at the latest.
- Enteric-CBD capsules (even CBD gummies) in the form of capsules guarantee the convenience of use and an accurately measured dose. However, the effect is felt no sooner than 30 minutes after taking it, depending on the body’s metabolic rate. The entire dose is metabolized.
- Inhalation of herbs and CBD crystals – for inhalation, special devices called inhalers or vaporizers are used, which heat CBD and other substances to the appropriate temperature, which releases them in the form of vapor. The inhaler prevents combustion, so no tar is released, eliminating the risk of smoke damage as in the case of regular smoking.
- CBD cosmetics for the skin – like any other CBD substance- can also be used externally. The absorption and permeability through the skin are certainly not as high as the other methods, as the skin is a certain barrier.
- CBD suppositories rectally – one of the least frequently used methods, mainly due to the inconvenience of application. Suppositories, thanks to their high bioavailability, guarantee quick absorption into the blood but bypassing metabolism in the digestive system.
CBD is considered a safe substance. Its toxicity is low, but this does not mean that our body will not react negatively. The possible side effects are nausea, diarrhea, and changes in appetite and weight. Many researchers emphasize that the effects of CBD vape oil use are unknown.
Using CBD along with other medications
In the case of chronically ill people and therefore take a lot of medications, be very careful when using, for example, herbs or supplements. The active compounds contained in them can affect the metabolism and the behavior of other substances in the body, including drugs. For this reason, when using multiple supplements, we can make the treatment ineffective or unsafe.
The same is true of CBD, which is often used as an adjunct to therapy. Chronically ill patients taking additional CBD experienced side effects more frequently. These are usually symptoms such as increased transaminases (liver burden), drowsiness, sleep disturbances, frequent infections, or anemia. Therefore, consult your doctor before using CBD.
How to use CBD oil?
The packaging of the product usually shows the appropriate number of drops that we can take a day. In supporting the therapy of certain diseases, it is recommended to gradually increase the dose, e.g., by one drop more every day, until a satisfactory effect is achieved – symptoms decrease. If you want to use CBD during therapy, it is best to discuss this with your doctor. It will help you choose the right concentration of CBD hemp oil and dose.
CBD oil is sprinkled under the tongue. Thanks to the extensive network of blood vessels, substances are absorbed within minutes.
What do we need to remember before using CBD oil?
First of all, let’s keep in mind that our knowledge of CBD’s effects, effectiveness, and safety is still being developed. The available studies are often animal or small group experiments. As the results are promising, we can be sure that science will provide us with new and more comprehensive information.
CBD oils are not drugs. No organ controls the production, purity, and content of individual substances in these products. Therefore, when choosing a specific preparation, you should not be influenced by the price and reach for products from well-known, proven manufacturers. Cheap products imported from untested sources can be unsafe or, at best, mixed (they may not contain CBD at all).